HLA-antigens and immunity to insulin in insulin-dependent diabetics with or without diabetic neuropathy.
作者： T. Scheinin , E. Matikainen , L. Groop , M. Lepäntalo , S. Koskimies
DOI: 10.3109/00365518809167503
关键词:
摘要: In order to define genetic, immunological and metabolic risk factors markers associated with diabetic neuropathy (DN) 47 insulin-dependent patients were compared 30 age-matched diabetes mellitus (IDDM) without neuropathy. Patients more often had proliferative retinopathy Albustixr` positive proteinuria than Judged by haemoglobin A1 (HbA1) concentrations measured during the preceding two years glycaemic control was worse in The frequency of HLA-antigens DR3, DR4, DR3/DR4. B8, B15 increased those DR2 B7 decreased patients. any these did not differ or There no significant differences frequencies insulin antibodies responses antigens between Howev...
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