In silico models for B-cell epitope recognition and signaling.

摘要: Tremendous technological advances in peptide synthesis and modification recent years have resolved the major limitations of peptide-based vaccines. B-cell epitopes are components these vaccines (besides having other biological applications). Researchers been developing silico or computational models for prediction both linear conformational epitopes, enabling immunologists clinicians to identify most promising characterization laboratory. Attempts also ongoing systems biology delineate signaling networks immune cells. Here we present all possible developed thus far areas.