摘要: Obesity is one of the most common medical problems in United States and a risk factor for illnesses such as hypertension, diabetes, degenerative arthritis myocardial infarction. It cause significant morbidity mortality generates great social financial costs. defined body mass index greater than 30. Many patients accomplish weight loss with diet, exercise lifestyle modification. Others require more aggressive therapy. Weight medications may be appropriate use selected who meet definition obesity or are overweight comorbid conditions. Medications formulated to reduce energy intake, increase output decrease absorption nutrients. Drugs cannot replace modification, which remain cornerstones treatment. Two new agents, sibutramine orlistat, exhibit novel mechanisms action avoid some side effects that occurred earlier drugs. Sibutramine acts block uptake serotonin, norepinephrine dopamine, while orlistat decreases fat intestines.
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