Cardiorespiratory and anesthetic effects of combined alfaxalone, butorphanol, and medetomidine in Thoroughbred horses.

摘要: This study evaluated induction of anesthesia and cardiorespiratory anesthetic effects during maintained with the combination alfaxalone, medetomidine, butorphanol. Alfaxalone (1.0 mg/kg) was administered to induce after premedication medetomidine (7.0 µg/kg), butorphanol (25 midazolam (50 µg/kg) in six Thoroughbred horses. Intravenous general alfaxalone (2.0 mg/(kg∙hr)), (5.0 µg/(kg∙hr)), (30 µg/(kg∙hr)) for 60 min. Electrical stimulation upper oral mucosa used assess depth at 10 min intervals anesthesia. Heart rate (HR), respiratory (RR), mean arterial pressure (MAP) were measured. All horses became recumbent within 1 administration. Induction scores 5 (best) five 4 one horse. During 60-min anesthesia, average HR, RR, MAP 35.8 ± 2.6 beat/min, 4.7 0.6 breath/min, 129 3 mmHg, respectively. No horse moved electrical stimulation; however, two experienced apnea (no respiration min). Recovery four These results suggest that is effective maintenance analgesia when combined Thoroughbreds. However, depression might require support.