Neuropsychological abnormalities in cirrhosis include learning impairment

摘要: Background/Aims Minimal hepatic encephalopathy is a neurocognitive disorder secondary to liver failure that characterized by pattern of subcortical impairment. The most conspicuous neuropsychological abnormalities are on attention and psychomotor tests; memory has been inconsistently implicated. We designed study assess the presence in cirrhotic patients effects transplantation. Methods Ninety-seven cirrhotics without overt underwent assessment, including Auditory Verbal Learning Memory Test. results were compared those healthy controls ( n =75) assessment was repeated at one year follow-up =33) or after transplantation =23). Results Cirrhotic exhibited multiple abnormalities, several disturbances test: learning, long-term recognition. Abnormalities recognition corrected adjusting for learning correlated impairment parameters function. Neuropsychological indexes following did not differ from controls. Repeated testing have major effect tests subjects non-transplanted cirrhotics. Conclusions present with abnormalities. This abnormality consistent deficit minimal encephalopathy.