Erythrocyte surface sialic acid depletion as predisposing factor to erythrocyte destruction in sheep experimental model of African trypanosomosis: a preliminary report.

作者: A. J. Nok , S. Adamu , N. D. G. Ibrahim , K. A. N. Esievo , N. M. Useh

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摘要: Summary: Changes in erythrocyte surface (ESSA) and free serum sialic (FSSA) profiles that could occur sequel to trypano-some infection with consequent destruction of red blood cells by mononuclear phagocytic system were investigated an experiment which 8 sheep infected Trypanosoma congolense ( T. ), while six other served as uninfected controls. The caused rapid decline ESSA concentration packed cell vol-ume (PCV) sheep. Concomitantly, rise mean FSSA was observed the Major periods greatest increase coincided period high-est parasitaemia levels. stabilized aged but this parameter remained at comparatively lower levels than control relative pre-infection value on day 0 infection. This level

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