Thrombocytopenia post liver transplantation

摘要: This study reports that thrombocytopenia is a universal phenomenon post hepatic transplantation. In 53 consecutive adult patients undergoing liver transplantation the platelet count fell by mean of 63% (157 × 10 9 /l to 50 /l). The reached nadir at Day 5 post-transplant but returned pre-operative levels 14. Non-parametric regression analysis found count, blood transfusion requirements and maximum post-operative ALT values were independent predictors percentage fall in count. No correlation was seen with length graft cold ischaemic time or use University Wisconsin (UW) solution. day correlated bilirubin ALT, UW Maximum also an predictor It observed who did not survive hospital admission had lower counts these return survival. Severe associated cerebral haemorrhage 3 patients. report provides evidence allograft dysfunction (maximum and/or AST/ALT) most consistent although exact mechanism(s) changes remain uncertain.