Prevalence and incidence of schizophrenia spectrum disorders: implications for prevention.
作者： Assen Jablensky
DOI: 10.1080/000486700219
关键词:
摘要: Objective: This paper reviews the historical and conceptual background to proposals about prevention of schizophrenia through intervention targeting asymptomatic, high-risk individuals. It also examines outcomes a hypothetical model based on two-stage risk segmenting approach.Method: The assumptions parameters used in are derived from actual epidemiological clinical research. two criteria selected are: (i) genetic (having parent with schizophrenia); (ii) neurocognitive deficit (abnormal performance Continuous Performance Task, CPT). factors applied screening program covering population 100 000.Results: At end second stage using search for preventable cases will have correctly identified only three out 20 ‘true’ incorrectly assigned treatment non-cases. great majority people at who event...
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