Spinal NF-kB activation induces COX-2 upregulation and contributes to inflammatory pain hypersensitivity

作者: Kyung-Min Lee , Bong-Seok Kang , Hye-Lim Lee , Sun-Joo Son , Sung-Hun Hwang

DOI: 10.1111/J.0953-816X.2004.03441.X

关键词:

摘要: … Moreover, the transcription factor, nuclear factor-kappa B (NF-kB), regulates the … spinal NF-kB in the induction of inflammatory pain hypersensitivity, we examined whether activated NF-…

参考文章(26)
Z. Shen, J. Peedikayil, G.K. Olson, P.D. Siebert, Y. Fang, Multiple transcription factor profiling by enzyme-linked immunoassay. BioTechniques. ,vol. 32, pp. 1168- 1177 ,(2002) , 10.2144/02325DD07
Tarek A. Samad, Kimberly A. Moore, Adam Sapirstein, Sara Billet, Andrew Allchorne, Stephen Poole, Joseph V. Bonventre, Clifford J. Woolf, Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity Nature. ,vol. 410, pp. 471- 475 ,(2001) , 10.1038/35068566
M.Y. Chiang, H. Chan, M.A. Zounes, S.M. Freier, W.F. Lima, C.F. Bennett, Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. Journal of Biological Chemistry. ,vol. 266, pp. 18162- 18171 ,(1991) , 10.1016/S0021-9258(18)55250-9
C Kaltschmidt, B Kaltschmidt, H Neumann, H Wekerle, P A Baeuerle, Constitutive NF-kappa B activity in neurons. Molecular and Cellular Biology. ,vol. 14, pp. 3981- 3992 ,(1994) , 10.1128/MCB.14.6.3981
Chuen-Mao Yang, Chin-Sung Chien, Li-Der Hsiao, Shu-Fen Luo, Chuan-Chwan Wang, Interleukin-1β-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-κB pathways in canine tracheal smooth muscle cells Cellular Signalling. ,vol. 14, pp. 899- 911 ,(2002) , 10.1016/S0898-6568(02)00037-2
Horacio Vanegas, Hans-Georg Schaible, Prostaglandins and cycloxygenases in the spinal cord Progress in Neurobiology. ,vol. 64, pp. 327- 363 ,(2001) , 10.1016/S0301-0082(00)00063-0
Chin-Feng Chan, Wei-Zen Sun, Jen-Kun Lin, Shoei-Yn Lin-Shiau, Activation of transcription factors of nuclear factor kappa B, activator protein-1 and octamer factors in hyperalgesia. European Journal of Pharmacology. ,vol. 402, pp. 61- 68 ,(2000) , 10.1016/S0014-2999(00)00431-3
K. Hargreaves, R. Dubner, F. Brown, C. Flores, J. Joris, A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. ,vol. 32, pp. 77- 88 ,(1988) , 10.1016/0304-3959(88)90026-7