Biomimetic phosphate assay based on nanopores obtained by immobilization of zirconium(IV) on a film of polyethyleneimine

摘要: A biomimetic ion-responsive single nanopore sensor was constructed by immobilizing zirconium(IV) ion on a film of poly(ethylene terephthalate) whose surface modified with polyethyleneimine (PEI) to form nanopores. PEI is an excellent metal-chelating ligand that initially the membrane through amidation. The Zr-chelated responds inorganic phosphate change in current–voltage plot. This due reversal charge from positive negative after binding tip channel. Inorganic can be quantified measurement extent rectification. limit detection method 118 nM, and response linear 0 40 μM concentration range. formation Zr(IV)/phosphate system corroborated X-ray photoelectron spectroscopy characterization. synthetic display selectivity, high sensitivity wide range for phosphate. accuracy applicability nanopore-based scheme proven successful determination (spiked) lake water cola drink.