Conglutinin and immunoconglutinins.

摘要: Publisher Summary The chapter focuses on conglutinin and immunoconglutinins. Conglutinin is a remarkable serum protein peculiar to ruminants, which interacts with fixed C’3 of all species tested or polysaccharide component yeasts some related organisms. It highly asymmetric molecule its hydrodynamic chemical properties distinguish it sharply from the immunoglobulins. Conglutinogen found in complement as well yeast—both cell wall microsomal fraction—and certain Immunoconglutinins are group predominantly immunoglobulin M (IgM) autoantibodies formed response antigenic stimulation by components an animal's own complement-commonly C’3, but sometimes C’4. They heterogeneous their reactivity. bulk immunoconglutinins (I-K) anti-C’3, anti-C’4 I-K has also been identified. mammalian chickens. Many types cell, if sensitized complement-fixing antibody, may be conglutinated presence (K). This “direct conglutination reaction” therefore provides test for antibody. aggregation produced so strong that reaction special application detection antibodies against poorly agglutinable, freshly isolated, bacterial suspensions.