Role of platelet function in symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
作者： H Ohkuma , S Suzuki , M Kimura , E Sobata
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摘要: To evaluate the role of platelet function in pathogenesis cerebral vasospasm, we compared sequential changes aggregability and beta-thromboglobulin thromboxane B2 concentrations blood samples from internal jugular peripheral vein 13 patients with aneurysmal subarachnoid hemorrhage. Platelet tended to be enhanced during days 0-1 but recovered normal range 2-4. After day 5, showed various patterns depending on presence symptomatic vasospasm. In without were relatively minor, or slightly high values. Patients vasospasm already early stage The concentration increased several after onset reaching 80 ng/ml more a poor prognosis. Two five markedly 8. These results suggest that activates platelets promotes resulting tendency for thrombus formation may affect patient's prognosis advanced stage.
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