Metal-free cascade reactions of aldehydes and primary amines for the synthesis of 1,3,4-trisubstituted pyrroles
作者： Yong Gao , Changfeng Hu , Jie-Ping Wan , Chengping Wen
DOI: 10.1016/J.TETLET.2016.09.063
关键词:
摘要: Abstract The synthesis of 1,3,4-trisubstituted pyrroles has been realized via the cascade reactions phenylacetaldehydes and primary amines. It is first time that this annulation involving construction one new C–C two C–N bonds successfully conducted under metal-free conditions.
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