Laryngeal cancer in nondrinker nonsmoker young patients: a distinct pathological entity?

摘要: PURPOSE OF REVIEW Laryngeal cancer published literature was reviewed, with emphasis on reporting young patients (<40 years). With such information, to comment the evidence or not, that patients, should they be nondrinkers and nonsmokers, have a differing cause genetic/molecular profile rather than spectrum of classic disease. RECENT FINDINGS Head neck in is documented at rate 0.4-3.6%, laryngeal being identified less 2% all diagnosed head overall. nondrinking nonsmokers has been reported from tertiary clinical hospitals only, few having diagnosis cancer, thus their drinking smoking habits may considered suspect. Most molecular genetic studies who probably had varying degrees habits, nonlaryngeal sites. These finding confirmed 'pure group' years) confirm nondrinkers, nonsmokers. SUMMARY Many authors nonsmoking likely explained by some level abnormality histological distinct group. However, because low incidence rapid development sequencing, project completed requires greater collaboration between clinicians pathologists.