Dietary Fat Intake and Carotid Artery Wall Thickness: The Atherosclerosis Risk in Communities (ARIC) Study

摘要: Associations between atherosclerosis and dietary fat cholesterol have been demonstrated in numerous animal experiments. The relation these components has not previously reported a population-based study among human beings. associations of with carotid artery wall thickness (atherosclerosis) were investigated study, the Atherosclerosis Risk Communities (ARIC) Study, from 1987 to 1989. Participants 2,095 black women, 5,146 white 1,318 men 4,589 men, aged 45-64 years, recruited four US communities: Jackson, Mississippi; Forsyth County, North Carolina; Washington Maryland; Minneapolis, Minnesota. Habitual diet was assessed food frequency questionnaire. Wall measured B-mode ultrasound. After adjustment for age energy intake, fat, saturated monounsaturated cholesterol, Keys' score positively related thickness, while vegetable polyunsaturated inversely thickness. These persisted after further smoking hypertension consistent across race sex groups. Thus, elements habitual intake consistently associated compatible their putatively atherogenic antiatherogenic properties.