作者: M. P. Herring , M. H. Sailors , M. S. Bray
DOI: 10.1111/OBR.12089
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摘要: Physical activity and exercise play critical roles in energy balance. While many interventions targeted at increasing physical have demonstrated efficacy promoting weight loss or maintenance the short term, long term adherence to such programmes is not frequently observed. Numerous factors been examined for their ability predict and/or influence adherence. Although has a strong genetic component both animals humans, few studies association between variation In this review, we provide detailed overview of non-genetic predictors exercise. addition, report results analysis 26 single nucleotide polymorphisms six candidate genes adherence, duration, intensity total dose young adults from Training Interventions Genetics Exercise Response (TIGER) Study. Based on animal human research, neural signalling pleasure/reward systems brain may drive large part propensity be physically active adhere an programme. Adherence/compliance research other fields inform future investigation genetics