Genome-Wide Epigenetic Regulation of Gene Transcription in Maize Seeds.

作者: Xiaoduo Lu , Weixuan Wang , Wen Ren , Zhenguang Chai , Wenzhu Guo

DOI: 10.1371/JOURNAL.PONE.0139582

关键词:

摘要: Background Epigenetic regulation is well recognized for its importance in gene expression organisms. DNA methylation, an important epigenetic mark, has received enormous attention recent years as it’s a key player many biological processes. It remains unclear how methylation contributes to transcription maize seeds. Here, we take advantage of technologies examine the genome-wide association with four types sequences, including protein-coding genes, pseudogenes, transposable elements, and repeats embryo endosperm, respectively. Results The CG, CHG CHH contexts plays different roles control expression. Methylation around start sites stop regions genes negatively correlated, but bodies positively level. The upstream are enriched 24-nt siRNAs contain high levels which correlated analysis sequence content within CHG, or reveals that only affected by local from Arabidopsis. Conclusions In summary, conclude methylation-regulated varies parts specific seeds differs other plant species. Our study helps people better understand viewpoint transcriptional controlled one factors influencing transcription, associated small RNAs.

参考文章(62)
Jeffrey L. Bennetzen, Sarah Hake, Handbook of maize : genetics and genomics Springer. ,(2009)
I. A. Maksakova, D. L. Mager, D. Reiss, Keeping active endogenous retroviral-like elements in check: the epigenetic perspective. Cellular and Molecular Life Sciences. ,vol. 65, pp. 3329- 3347 ,(2008) , 10.1007/S00018-008-8494-3
H Xiang, DJ Cheng, Y Dong, SC Guo, GW Guo, YH He, RQ Li, JD Zhu, QH Guo, J Wang, JF Sun, XQ Zhang, Y Lin, YR Li, QY Xia, GJ Zhang, L Zhao, XY Zhou, W Wang, LJ Ma, KL Ma, Ja Yu, HY Zhang, D Li, QA Chen, MW Li, JH Jiang, X Li, FY Dai, S Beck, K Kristiansen, MZ Ye, YX Zhao, Single base-resolution methylome of the silkworm reveals a sparse epigenomic map (vol 28, pg 516, 2010) Nature Biotechnology. ,(2010)
Ian R. Henderson, Steven E. Jacobsen, Epigenetic inheritance in plants Nature. ,vol. 447, pp. 418- 424 ,(2007) , 10.1038/NATURE05917
Tamar Hashimshony, Jianmin Zhang, Ilana Keshet, Michael Bustin, Howard Cedar, The role of DNA methylation in setting up chromatin structure during development. Nature Genetics. ,vol. 34, pp. 187- 192 ,(2003) , 10.1038/NG1158
Wolfgang Goettel, Joachim Messing, Epiallele biogenesis in maize. Gene. ,vol. 516, pp. 8- 23 ,(2013) , 10.1016/J.GENE.2012.12.034
Xiaodong Cheng, Robert M. Blumenthal, Mammalian DNA Methyltransferases: A Structural Perspective Structure. ,vol. 16, pp. 341- 350 ,(2008) , 10.1016/J.STR.2008.01.004
Shawn J. Cokus, Suhua Feng, Xiaoyu Zhang, Zugen Chen, Barry Merriman, Christian D. Haudenschild, Sriharsa Pradhan, Stanley F. Nelson, Matteo Pellegrini, Steven E. Jacobsen, Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning Nature. ,vol. 452, pp. 215- 219 ,(2008) , 10.1038/NATURE06745
Silin Zhong, Zhangjun Fei, Yun-Ru Chen, Yi Zheng, Mingyun Huang, Julia Vrebalov, Ryan McQuinn, Nigel Gapper, Bao Liu, Jenny Xiang, Ying Shao, James J Giovannoni, Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening Nature Biotechnology. ,vol. 31, pp. 154- 159 ,(2013) , 10.1038/NBT.2462
L. Poliseno, Pseudogenes: newly discovered players in human cancer. Science Signaling. ,vol. 5, pp. 2002858- ,(2012) , 10.1126/SCISIGNAL.2002858