Modulation of immune response by non-peptide binding stress response polypeptides

作者: Christopher V. Nicchitta , Julie C. Baker-LePain

DOI:

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摘要: A recombinant stress response polypeptide that lacks an antigen binding domain, and methods for using the to elicit immune response, example anti-tumor in a subject.

参考文章(216)
Wadih Arap, Renata Pasqualini, Erkki Ruoslahti, Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model Science. ,vol. 279, pp. 377- 380 ,(1998) , 10.1126/SCIENCE.279.5349.377
P Tam, M Monck, D Lee, O Ludkovski, E C Leng, K Clow, H Stark, P Scherrer, R W Graham, P R Cullis, Stabilized plasmid-lipid particles for systemic gene therapy Gene Therapy. ,vol. 7, pp. 1867- 1874 ,(2000) , 10.1038/SJ.GT.3301308
Gunnar von Heijne, The signal peptide. The Journal of Membrane Biology. ,vol. 115, pp. 195- 201 ,(1990) , 10.1007/BF01868635
Eamonn Coveney, Bryan Clary, Michelle Iacobucci, Ramila Philip, Kim Lyerly, Active immunotherapy with transiently transfected cytokine-secreting tumor cells inhibits breast cancer metastases in tumor-bearing animals Surgery. ,vol. 120, pp. 265- 273 ,(1996) , 10.1016/S0039-6060(96)80297-2
Pamela A. Wearsch, Christopher V. Nicchitta, Interaction of Endoplasmic Reticulum Chaperone GRP94 with Peptide Substrates Is Adenine Nucleotide-independent Journal of Biological Chemistry. ,vol. 272, pp. 5152- 5156 ,(1997) , 10.1074/JBC.272.8.5152
Gian Maria Rossolini, Stefania Cresti, Angela Ingianni, Paola Cattani, Maria Letizia Riccio, Giuseppe Satta, Use of deoxyinosine-containing primers vs degenerate primers for polymerase chain reaction based on ambiguous sequence information. Molecular and Cellular Probes. ,vol. 8, pp. 91- 98 ,(1994) , 10.1006/MCPR.1994.1013
Ralph R. Weichselbaum, Dennis Hallahan, Zvi Fuks, Donald Kufe, Radiation induction of immediate early genes: Effectors of the radiation-stress response International Journal of Radiation Oncology Biology Physics. ,vol. 30, pp. 229- 234 ,(1994) , 10.1016/0360-3016(94)90539-8
S Altschula, Warren Gisha, Webb Millerb, E Meyersc, D Lipmana, None, Basic Local Alignment Search Tool Journal of Molecular Biology. ,vol. 215, pp. 403- 410 ,(1990) , 10.1016/S0022-2836(05)80360-2
THOMAS F. BUMOL, PHILIP MARDER, SONJA V. DeHERDT, MICHAEL J. BOROWITZ, LYNN D. APELGREN, Characterization of the human tumor and normal tissue reactivity of the KS1/4 monoclonal antibody. Hybridoma. ,vol. 7, pp. 407- 415 ,(1988) , 10.1089/HYB.1988.7.407
Eckhard Lammert, Stefan Stevanović, Josef Brunner, Hans-Georg Rammensee, Hansjörg Schild, Protein disulfide isomerase is the dominant acceptor for peptides translocated into the endoplasmic reticulum European Journal of Immunology. ,vol. 27, pp. 1685- 1690 ,(1997) , 10.1002/EJI.1830270714