作者: S. V. Razin , A. A. Gavrilov , S. V. Ulyanov
DOI: 10.1134/S0026893315020119
关键词:
摘要: The eukaryotic genomic regulatory elements that control transcription are considered. review describes the functional anatomy of tissuespecific and housekeeping gene promoters, current methods to predict identify enhancers, role insulators play in enhancer-promoter communication maintenance epigenetic status genome domains. relationship between topology inter� phase chromatin regulation is outlined. Particular attention paid recent data obtained via highthroughput sequencing primary tr anscripts genomewide analysis histone modi� fications. DOI: 10.1134/S0026893315020119