AROMATASE INHIBITORS FOR MALE INFERTILITY

作者: Jay D. Raman , Peter N. Schlegel

DOI: 10.1016/S0022-5347(01)69099-2

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摘要: Purpose: Testosterone-to-estradiol ratio levels in infertile men improve during treatment with the aromatase inhibitor, testolactone, and resulting changes semen parameters. We evaluated effect of anastrozole, a more selective on hormonal profiles abnormal baseline testosterone-to-estradiol ratios.Materials Methods: A total 140 subfertile ratios were treated 100 to 200 mg. testolactone daily or 1 anastrozole daily. Changes testosterone, estradiol, parameters therapy. The obesity, diagnosis Klinefelter syndrome, presence varicocele and/or history repair results was studied.Results: Men had an increase therapy (mean plus minus standard error mean 5.3 ± 0.2 versus 12.4 1.1, p <0.001). This ...

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