Innate lymphoid cells and fibrotic regulation

摘要: Innate lymphoid cells (ILCs) are innate immune that do not possess B or T cell receptors but belong to the lineage. While these have yet been extensively investigated since their classification as a homogenous group, emerging evidence suggests they exert significant regulatory roles in both tissue remodelling and inflammation, therefore, also involved fibrotic regulation. The following review will serve outline transcription factors, surface markers, cytokines define each subgroup, process by which differentiate. Furthermore, diverse functions of non-pathogenic states be discussed, addition interactions between ILCs other system, adaptive, how pathways can elicit pro- anti-inflammatory -fibrotic effects varying tissues.