Structural and catalytic roles of metal ions in RNA.

摘要: The discovery of ribozymes triggered a huge interest in the chemistry and biology RNAs. Much recently made progress focusing on metal ions is addressed Volume 9. This book, written by 28 internationally recognized experts, provides most up-to-date view it thus special relevance for colleagues teaching courses biological inorganic researchers dealing, e.g., with nucleic acids, gene expression, enzymology, but also those analytical bioinorganic or biophysics. Structural Catalytic Roles Metal Ions RNA describes ion-binding motives, methods to detect characterize ion binding sites, role folding catalysis. It deals diffuse binding, quadruplexes, regulation riboswitches, ribozymes, including artificial ribozymes. ribosome, redox cofactors, as well kinetically inert are considered.