Metal Ion-Promoted Conformational Changes of Oligonucleotides

作者: Bernhard Spingler

DOI: 10.1007/978-94-007-2172-2_3

关键词: DNAChemistryCrystal structureCircular dichroismMetal ions in aqueous solutionConformational changeRNAOligonucleotideComputational chemistryMetal

摘要: The review will discuss the influence of metal ions on conformational changes oligonucleotides. First, a short definition torsion angles is given, followed by concise yet critical overview commonly applied experimental techniques. Finally, possible role metals upon following oligonucleotides discussed: (i) denaturation double-strands, (ii) transition from B- to A-DNA, (iii) right- left-handed DNA and RNA, (iv) condensation, (v) other changes. We conclude with summary outlook.

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