Practical Nuclear Medicine and Utility of Phantoms for Internal Dosimetry: XCAT Compared with Zubal

作者: Maryam Fallahpoor , Mehrshad Abbasi , Faraz Kalantari , Ali Asghar Parach , Anando Sen

DOI: 10.1093/RPD/NCW115

关键词:

摘要: Purpose The absorbed doses for two radioisotopes, 99mTc and 131I, between previously validated Zubal phantom the recently developed XCAT were compared. Materials methods GATE Monte Carlo code was used to simulate statistical process of radiation. A with voxel matrix sizes similar a standard generated. According Medical International Radiation Dose formalism, specific fraction (SAF) values photons S-factors beta particles tabulated. amounts calculated compared in different organs. Results differences gamma radiation doses, SAFs, are >50% adrenal from adrenal, pancreas thyroid thyroid, lung kidney, kidneys lungs kidneys. bladder bladder, kidney liver thyroid. size distances organs phantoms. Denoted SAF correspond organ geometries Conclusion results phantoms different. variations prohibit easy comparison or interchangeability dosimetry these

参考文章(25)
Thomas F. Budinger, Evelyn E. Watson, Robert Loevinger, MIRD primer for absorbed dose calculations ,(1988)
D. W. O. Rogers, Radhe Mohan, Questions for comparison of clinical Monte Carlo codes Springer, Berlin, Heidelberg. pp. 120- 122 ,(2000) , 10.1007/978-3-642-59758-9_44
A. A. Parach, H. Rajabi, A comparison between GATE4 results and MCNP4B published data for internal radiation dosimetry. Nuklearmedizin-nuclear Medicine. ,vol. 50, pp. 122- 133 ,(2011) , 10.3413/NUKMED-0363-10-10
W. P. Segars, G. Sturgeon, S. Mendonca, Jason Grimes, B. M. W. Tsui, 4D XCAT phantom for multimodality imaging research Medical Physics. ,vol. 37, pp. 4902- 4915 ,(2010) , 10.1118/1.3480985
Richard Taschereau, Arion F. Chatziioannou, Monte Carlo simulations of absorbed dose in a mouse phantom from 18‐fluorine compounds Medical Physics. ,vol. 34, pp. 1026- 1036 ,(2007) , 10.1118/1.2558115
Ludovic Ferrer, Nicolas Chouin, Abdalkader Bitar, Albert Lisbona, Manuel Bardiès, Implementing Dosimetry in GATE: Dose-Point Kernel Validation with GEANT4 4.8.1 Cancer Biotherapy and Radiopharmaceuticals. ,vol. 22, pp. 125- 129 ,(2007) , 10.1089/CBR.2007.304
W. E. Bolch, K. F. Eckerman, G. Sgouros, S. R. Thomas, MIRD Pamphlet No. 21: A Generalized Schema for Radiopharmaceutical Dosimetry—Standardization of Nomenclature The Journal of Nuclear Medicine. ,vol. 50, pp. 477- 484 ,(2009) , 10.2967/JNUMED.108.056036
Yuni K. Dewaraja, Scott J. Wilderman, Kenneth F. Koral, Mark S. Kaminski, Anca M. Avram, Use of integrated SPECT/CT imaging for tumor dosimetry in I-131 radioimmunotherapy: a pilot patient study. Cancer Biotherapy and Radiopharmaceuticals. ,vol. 24, pp. 417- 426 ,(2009) , 10.1089/CBR.2008.0568
S Marcatili, C Pettinato, S Daniels, G Lewis, P Edwards, S Fanti, E Spezi, Development and validation of RAYDOSE: a Geant4-based application for molecular radiotherapy. Physics in Medicine and Biology. ,vol. 58, pp. 2491- 2508 ,(2013) , 10.1088/0031-9155/58/8/2491
D. Strulab, G. Santin, D. Lazaro, V. Breton, C. Morel, GATE (geant4 application for tomographic emission): a PET/SPECT general-purpose simulation platform Nuclear Physics B - Proceedings Supplements. ,vol. 125, pp. 75- 79 ,(2003) , 10.1016/S0920-5632(03)90969-8