Age-related changes in aortic and mitral valve thickness: implications for two-dimensional echocardiography based on an autopsy study of 200 normal human hearts

摘要: The thicknesses at 3 sites of each aortic cusp (nodule, closing edge and middle part) 2 both mitral leaflets (closing clear zone) were measured in 200 autopsy specimens normal hearts, evenly distributed by age sex. There no significant correlations between valvular thickness height, weight, heart weight or body surface area. mean site was not different men women but increased significantly with (p less than 0.001). For groups (less 20, 20 to 59 greater equal 60 years), the corresponding (mm) nodule 0.67, 0.87 1.42; those for anterior leaflet 1.30, 1.60 3.20; posterior 0.91, 1.13 2.04. valve, nearly twice as thick 0.001), least 25% thicker part Furthermore, right left cusps 0.05). leaflets, zone Moreover, along edges, These observations may be useful echocardiographic evaluations valve sclerosis elderly patients.