Premature onset of menstrual bleeding during ovulatory cycles in women with an intrauterine contraceptive device

摘要: Abstract Daily peripheral plasma levels of progesterone and estradiol were determined during 13 menstrual cycles in 10 women with an intrauterine contraceptive Copper-T device (model TCu 200) two a Lippes loop. As judged from the hormonal all ovulatory. Normal patterns found as compared to 34 ovulatory control for estradiol. However, relation patterns, bleeding usually started about days earlier than cycles, e.g., before had declined normally at onset bleeding. Similar findings made The premature shedding endometrium IUCD's may be due endometrial changes caused by device.