Fieber nach Zeckenstich: Klinik und Diagnostik von akuten Zeckenstich-assoziierten Infektionskrankheiten in der Nordostschweiz

摘要: BACKGROUND Different tick-borne infections can cause an acute febrile illness. The study objectives were to investigate the clinical manifestations and diagnosis of among patients who presented with fever after a tick-bite, detect newly described pathogens, including Ehrlichia, Babesia Rickettsia helvetica, in North-Eastern Switzerland. PATIENTS AND METHODS : We studied 75 (41 male, 34 female, median age 38 years, them 10 children) had within 3 weeks tick-bite. Paired sera tested for antibodies Borrelia burgdorferi, encephalitis virus, Anaplasma (Ehrlichia) phagocytophila, microti, B. divergens, helvetica. In addition, microscopy polymerase chain reaction was used Ehrlichia. Clinical data obtained at baseline 1 2 year follow-up. RESULTS Tick-borne confirmed or possible 36 (48 %) patients: 7 (9 Erythema migrans, 6 (8 other specific Lyme borreliosis, borreliosis presenting as non-specific illness, 8 (11 encephalitis, (10 granulocytic ehrlichiosis, microti infection traveler from US dual infections. serological findings suggesting past R. helvetica infection. CONCLUSION Among most frequently found. There no evidence babesiosis resident population. Serologic suggest that human ehrlichiosis may be endemic 50 % could diagnosed.