A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology

摘要: Anthracyclines are the mainstay of treatment a variety haematological malignancies and solid tumours. Unfortunately, clinical use these drugs is limited by cumulative, dose-related cardiotoxicity which may ultimately lead to severe irreversible form cardiomyopathy. Thus, there an increasing need for close cooperation among cardiologists, oncologists haemato-oncologists. As anthracyclines save lives, logical goal this cooperation, besides preventing or mitigating cardiotoxicity, promote acceptable balance between potential cardiac side effects vital benefit anticancer treatment. This manuscript, specifically addressed cardiologist who has not accumulated much experience in field cancer therapy, focuses on several topics, that old new mechanisms toxicity, late importance overall risk assessment, key role cardiology consult before starting pros cons primary secondary prevention programmes.