Cervical cancer patterns with automation‐assisted and conventional cytological screening: A randomized study

摘要: The purpose was to evaluate alternative cytological screening methods in population-based for cervical cancer up incidence and mortality outcome. Automation-assisted compared conventional a randomized design. study based on follow-up of 503,391 women invited the Finnish program during 1999-2003. endpoints were incident cancer, severe intraepithelial neoplasia deaths from cancer. One third had been randomly allocated automation-assisted two thirds cytology. Information obtained through 1999-2007 linkage between registry files. There altogether 3.2 million woman-years at risk, average time 6.3 years. no difference risk methods; relative (RR) control arm 1.00 (95% confidence interval [CI] = 0.76-1.29) among all 1.08 CI 0.76-1.51) who test negative entry. Comparing with nonscreened, RR 0.26, 95% 0.19-0.36 0.24 (0.13-0.43). Both valid screening. Because is rare our country, we cannot rule out small differences methods. Evidence increasing it thus feasible new large-scale programs