作者: Nick Golding , Anne L Wilson , Catherine L Moyes , Jorge Cano , David M Pigott
DOI: 10.1186/S12916-015-0491-4
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摘要: Vector-borne diseases cause a significant proportion of the overall burden disease across globe, accounting for over 10 % infectious diseases. Despite availability effective interventions many these diseases, lack resources prevents their control. Many existing vector control are known to be against multiple so combining programmes simultaneously tackle several could offer more cost-effective and therefore sustainable reductions. The highly successful cross-disease integration vaccine mass drug administration in low-resource settings acts precedent Whilst deliberate implementation has yet trialled on large scale, number examples ‘accidental’ suggest potential such an approach. Combining contemporary high-resolution global maps major vector-borne pathogens enables us quantify overlap distributions estimate populations jointly at risk Such analysis shows that 80 % population live regions world from one disease, than half world’s areas where least two different pose threat health. information co-endemicity with assessment methods allows highlight opportunities integration. Malaria, leishmaniasis, lymphatic filariasis, dengue prime candidates combined All four considerably there is growing body evidence effectiveness insecticide-treated nets, screens, curtains controlling all vectors. real-world can only evaluated by large-scale trials, but clear approach enable greater health benefit using limited funds available.