Pharmaceutical combinations for the treatment of cancer

作者: Luca Mologni , Carlo Gambacorti

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摘要: This invention relates to pharmaceutical compositions for the treatment of cancer comprising a src kinase inhibitor and an HDAC inhibitor. It also methods treating in mammal by administering comnbination with

参考文章(5)
Luca Mologni, Loredana Cleris, Vera Magistroni, Rocco Piazza, Frank Boschelli, Franca Formelli, Carlo Gambacorti-Passerini, Valproic acid enhances bosutinib cytotoxicity in colon cancer cells International Journal of Cancer. ,vol. 124, pp. 1990- 1996 ,(2009) , 10.1002/IJC.24158
Warren Fiskus, Michael Pranpat, Maria Balasis, Purva Bali, Veronica Estrella, Sandhya Kumaraswamy, Rekha Rao, Kathy Rocha, Bryan Herger, Francis Lee, Victoria Richon, Kapil Bhalla, Cotreatment with Vorinostat (Suberoylanilide Hydroxamic Acid) Enhances Activity of Dasatinib (BMS-354825) against Imatinib Mesylate–Sensitive or Imatinib Mesylate–Resistant Chronic Myelogenous Leukemia Cells Clinical Cancer Research. ,vol. 12, pp. 5869- 5878 ,(2006) , 10.1158/1078-0432.CCR-06-0980
Warren Fiskus, Michael Pranpat, Purva Bali, Maria Balasis, Sandhya Kumaraswamy, Sandhya Boyapalle, Kathy Rocha, Jie Wu, Francis Giles, Paul W. Manley, Peter Atadja, Kapil Bhalla, Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl–expressing human leukemia cells Blood. ,vol. 108, pp. 645- 652 ,(2006) , 10.1182/BLOOD-2005-11-4639
Francis Y. Lee, Kapil N. Bhalla, Method of treating chronic myelogenous leukemia cells ,(2007)