Targeting peptides that bind s. mutans, constructs comprising such peptides and uses thereof

作者: Randal H. Eckert , Pierre A. Kyme , Brian C. Varnum , Christopher W. Kaplan

DOI:

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摘要: In certain embodiments, novel targeting peptides that specifically/preferentially bind to S. mutans are provided. The can be attached effectors (e.g., detectable labels, drugs, antimicrobial peptides, etc.) form chimeric constructs for delivering the effector and/or into target organism. embodiments attached, e.g., used selectively inhibit kill and, when in oral cavity of a mammal, effective reduce incidence severity dental caries severit periodontal disease.

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