Correlation of Serum Soluble Fibrinogen-Like Protein 2 with Soluble FAS Ligand and Interferon Gamma in Egyptian Hepatitis C Virus-Infected Patients and Hepatocellular Carcinoma Patients.
作者： Mohamed El-Mesery , Mohammed El-Mowafy , Abdelaziz Elgaml , Laila F. Youssef , Sally Y. Abed
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摘要: Infection with hepatitis C virus (HCV) remains one of the serious human diseases worldwide, especially in Egypt, which can lead to cirrhosis or hepatocellular carcinoma (HCC). However, exact molecular mechanism HCC progress HCV-infected patients unclear. Soluble fibrinogen-like protein 2 (sFGL2) is a modulator immune response that secreted by T cells and inhibits maturation dendritic cell proliferation. In current study, serum sFGL2 levels were analyzed enzyme-linked immunosorbent assay (ELISA) technique 30 chronic (HCV group), (HCC 12 healthy individuals (control group). Moreover, soluble FAS ligand (sFASL) interferon gamma (IFN-γ) correlated levels. According our results, significantly elevated all HCV infection. showed lower than HCV-infected...
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