The Neurochemistry of Sleep and Wakefulness

作者: Helen A. Baghdoyan , Ralph Lydic

DOI: 10.1016/B978-0-12-374947-5.00057-2

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摘要: Publisher Summary This chapter focuses on the neurotransmitter and neu­romodulator systems that, when altered, causes disorders of sleep. Sleep occurs as two states, rapid eye movement (REM) non-rapid (NREM), these states are dis­tinct from each other one is wakefulness. NREM sleep REM oscillate with an ultradian frequency. Alternations between wakefulness modulated by circadian system homeostatic processes that regulate recovery restriction deprivation. The neurochemical bases homeo­static mechanisms regulates remains to be discovered. All placental, terrestrial mammals have traits similar those humans. Therefore, animal mod­els useful for providing insights into neuro­chemical neurophysiological generate Neural able now recognized play a role in loss caused anesthetic drugs recent advances concerning shared regulation anesthesia selectively reviewed.

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