摘要: Streptococcus agalactiae (group B streptococcus) is an important cause of disease in infants, pregnant women, the elderly and immunosuppressed adults. An effective vaccine likely to prevent majority infant (both early late onset), avoid limitations intrapartum antibiotic prophylaxis be cost effective. A number candidates, including capsular conjugate vaccines, have potential successful vaccines. Phase II human studies with vaccines been completed successfully. Issues yet resolved include safety acceptability vaccination during pregnancy, durability vaccine-derived immunity regulatory issues required for licensure.
expert-reviews.com参考文章(61)
A Schuchat, K M Zangwill, J D Wenger, Group B streptococcal disease in the United States, 1990: report from a multistate active surveillance system. MMWR. CDC surveillance summaries : Morbidity and mortality weekly report. CDC surveillance summaries / Centers for Disease Control. ,vol. 41, pp. 25- 32 ,(1992)
Sharon Hillier, Women Receiving Group B Streptococcus Serotype III Tetanus Toxoid (GBS III-TT) Vaccine Have Reducesd Vaginal and Rectal Acquisition of GBS Type III 47th Annual Meeting. ,(2009)
L C Paoletti, M R Wessels, A K Rodewald, A A Shroff, H J Jennings, D L Kasper, Neonatal mouse protection against infection with multiple group B streptococcal (GBS) serotypes by maternal immunization with a tetravalent GBS polysaccharide-tetanus toxoid conjugate vaccine Infection and Immunity. ,vol. 62, pp. 3236- 3243 ,(1994) , 10.1128/IAI.62.8.3236-3243.1994
, Albert J. Mifsud, Androulla Efstratiou, André Charlett, A. Christine McCartney, Early-onset neonatal group B streptococcal infection in London: 1990-1999. British Journal of Obstetrics and Gynaecology. ,vol. 111, pp. 1006- 1011 ,(2004) , 10.1111/J.1471-0528.2004.00225.X
José B López Sastre, Belen Fernández Colomer, GD Coto Cotallo, Antonio Ramos Aparicio, Trends in the epidemiology of neonatal sepsis of vertical transmission in the era of group B streptococcal prevention. Acta Paediatrica. ,vol. 94, pp. 451- 457 ,(2005) , 10.1111/J.1651-2227.2005.TB01917.X
D L Kasper, L C Paoletti, M R Wessels, H K Guttormsen, V J Carey, H J Jennings, C J Baker, Immune response to type III group B streptococcal polysaccharide-tetanus toxoid conjugate vaccine. Journal of Clinical Investigation. ,vol. 98, pp. 2308- 2314 ,(1996) , 10.1172/JCI119042
Immaculada Margarit, Cira Daniela Rinaudo, Cesira L. Galeotti, Domenico Maione, Claudia Ghezzo, Elena Buttazzoni, Roberto Rosini, Ylenia Runci, Marirosa Mora, Scilla Buccato, Massimiliano Pagani, Eleonora Tresoldi, Alberto Berardi, Roberta Creti, Carol J. Baker, John L. Telford, Guido Grandi, Preventing bacterial infections with pilus-based vaccines: the group B Streptococcus paradigm The Journal of Infectious Diseases. ,vol. 199, pp. 108- 115 ,(2009) , 10.1086/595564
Shabir A. Madhi, Kholeka Radebe, Heather Crewe-Brown, Carl E. Frasch, Guthrie Arakere, Mantoa Mokhachane, Alan Kimura, High burden of invasive Streptococcus agalactiae disease in South African infants. Annals of Tropical Paediatrics. ,vol. 23, pp. 15- 23 ,(2003) , 10.1179/000349803125002814
L. M Moses, P T Heath, A R Wilkinson, H E Jeffery, D Isaacs, Early onset group B streptococcal neonatal infection in Oxford 1985-96 Archives of Disease in Childhood-fetal and Neonatal Edition. ,vol. 79, ,(1998) , 10.1136/FN.79.2.F148
Debra L. Palazzi, Marcia A. Rench, Morven S. Edwards, Carol J. Baker, Use of Type V Group B Streptococcal Conjugate Vaccine in Adults 65–85 Years Old The Journal of Infectious Diseases. ,vol. 190, pp. 558- 564 ,(2004) , 10.1086/422010