作者: Alessandro Pezzini , Mario Grassi , Corrado Lodigiani , Rosalba Patella , Carlo Gandolfo
DOI: 10.1161/STROKEAHA.110.592246
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摘要: Background and Purpose—The mechanisms underlying the relationship between migraine ischemic stroke remain uncertain. The aim of present study was to investigate predictive value major cardiovascular risk factors, cardiac interatrial abnormalities, additional biological markers on subtypes in young adults with stroke. Methods—Ischemic patients aged 45 years or younger were consecutively enrolled as part Italian Project Stroke Young Adults. A comprehensive evaluation performed including assessment self-reported right-to-left shunt, genotyping detect factor V Leiden G20210A mutation prothrombin gene. Results—Nine hundred eighty-one (mean age, 36.0±7.6 years; 50.7% women) included. aura increased decreasing number factors (OR, 0.50; 95% CI, 0.24–0.99 for 2 more), increasing thrombophi...