The Prescription Opioid Epidemic: Repercussions on Pediatric Emergency Medicine
作者： Hallam M. Gugelmann , Lewis S. Nelson
DOI: 10.1016/J.CPEM.2012.10.002
关键词:
摘要: Among other developed and developing nations, the United States is experiencing an unprecedented epidemic of prescription opioid misuse. The clearly continues to have significant widespread adverse effects on pediatric adult populations alike. Prescription opioids had single greatest impact emergency department visits, with visits increasing by 101% from 2001 2008, 86% increase in rates admission, injury 92%. This article provides readers overview epidemiology, history, basic science, advocacy interventions associated this public health calamity. It discusses increased susceptibility young children these drugs neonatal abstinence syndrome, withdrawal syndrome. A multifaceted approach will be needed contain problem including comprehensive prescriber patient education, expanded drug monitoring programs, protection against accidental ingestion, law enforcement efforts, stringent regulation oversight pharmaceutical companies.
clinpedemergencymed.com参考文章(87)
Paul J Christo, Jing Wang, The influence of prescription monitoring programs on chronic pain management Pain Physician. ,vol. 12, pp. 507- 515 ,(2009)
Larry F. Chu, David Clark, Martin S. Angst, Henry McQuay, Acute Pain Management: Molecular Basis and Clinical Implications of Opioid Tolerance and Opioid-Induced Hyperalgesia Cambridge University Press. pp. 114- 144 ,(2009) , 10.1017/CBO9780511576706.012
Sukanya Mitra, MD, MAMS, Opioid-induced hyperalgesia: pathophysiology and clinical implications. Journal of opioid management. ,vol. 4, pp. 123- 130 ,(2018) , 10.5055/JOM.2008.0017
Pampati, Manchikanti L, Fellows B, Ailinani H, Therapeutic use, abuse, and nonmedical use of opioids: a ten-year perspective Pain Physician. ,vol. 13, pp. 401- 435 ,(2010) , 10.36076/PPJ.2010/13/401
James M. Walker, Robert J. Farney, Steven M. Rhondeau, Kathleen M Boyle, Karen Valentine, Tom V. Cloward, Kevin C. Shilling, Chronic Opioid Use is a Risk Factor for the Development of Central Sleep Apnea and Ataxic Breathing Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. ,vol. 3, pp. 455- 461 ,(2007) , 10.5664/JCSM.26908
Leonard J. Paulozzi, Rose A. Rudd, Karin A. Mack, Christopher M. Jones, Vital Signs: Overdoses of Prescription Opioid Pain Relievers - United States, 1999-2008 Morbidity and Mortality Weekly. ,vol. 60, pp. 1487- ,(2011)
Hardman JG Ed, Goodman & Gilman's The Pharmacological Basis of Therapeutics ,(1985)
Lewis R. Goldfrank, Goldfrank's Toxicologic emergencies ,(1986)
Addiction rare in patients treated with narcotics. The New England Journal of Medicine. ,vol. 302, pp. 123- ,(1980) , 10.1056/NEJM198001103020221
Leonard J. Paulozzi, Richard H. Weisler, Ashwin A. Patkar, A national epidemic of unintentional prescription opioid overdose deaths: how physicians can help control it. The Journal of Clinical Psychiatry. ,vol. 72, pp. 589- 592 ,(2011) , 10.4088/JCP.10COM06560