Survival Following Recurrence in Stage II and III Colon Cancer: Findings From the ACCENT Data Set
作者： Michael J O'Connell , Megan E Campbell , Richard M Goldberg , Axel Grothey , Jean-François Seitz
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摘要: Purpose This study was undertaken to examine five possible prognostic factors in patients with recurrent stage II and III colon cancer: time from randomization on an adjuvant therapy clinical trial tumor recurrence ( 4 years), initial (II v III), treatment (fluorouracil [FU]-based surgery alone), the era which patient entered (1978 1985, 1986 1992, 1993 1999), age at recurrence. Methods The Adjuvant Colon Cancer End Points (ACCENT) data set analyzed using univariate multivariate Cox proportional hazards models, stratified by study. Results 5,722 (32.9%) of 17,381 experienced Median survival following 13.3 months. Time highly (P < .0001). Longer seen versus disease ....
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