Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.

作者: David Cunningham , Yves Humblet , Salvatore Siena , David Khayat , Harry Bleiberg

DOI: 10.1056/NEJMOA033025

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摘要: … Cetuximab is a monoclonal antibody that specifically blocks the EGFR. We compared the efficacy of cetuximab in combination with irinotecan with that of cetuximab alone in metastatic …

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