Non-phosphorous-linked oligomeric compounds and their use in gene modulation

作者: Anne B. Eldrup , Stanley T. Crooke , Muthiah Manoharan , Balkrishen Bhat , Brenda F. Baker

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摘要: Oligomer compositions comprising first and second oligomers are provided wherein at least a portion of the oligomer is capable hybridizing with oligomer, complementary to capble selected target nucleic acid, one or includes two nucleoside having modified non-phosphorous-containing internucleoside linkage. Oligomer/protein also an acid protein RNA-induced silencing complex (RISC), nucleosides has

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