Cytogenetic and teratological effects of mancozeb pre natal exposure on rats

摘要: Studies were conducted on the dam’s fertility and pup viability, litter physical motor development chromosomal analysis with female rats exposed to different concentrations of mancozeb, at initial organogenesis periods pregnancy. The exposure did not interfere pregnant females or their estrous cycle but resulted in retarded development, exception vaginal opening tests descent; which advance. body weight was affected. examination swimming performance indicated an impairment a posterior recovery. observed chromosome damage dams pups found enhance fungicide’s concentration. results obtained led conclusion that even absence maternal signs toxicity, mancozeb could be related some genetic teratogenic risk population exposed.