Effect of Dithiocarbamate-Type Chemicals on the Nervous System of Rats
作者： K. Thuránszky , I. Kiss , Margit Botos , A. Szebeni
DOI: 10.1007/978-3-642-68511-8_23
关键词: Chemistry 、 Norepinephrine 、 Rat brain 、 Electrophysiology 、 Electroencephalography 、 Pharmacology 、 Dopamine 、 Nervous system 、 Dithiocarbamate 、 Assay
摘要: Neurotoxic effect of some dithiocarbamate- and thiuram-disulphide-type chemicals as well CS2 were examined on rat brain behaviour. A significant reduction the orientation hypermotility at same time a depression subcortical EEG activity observed. The biochemical assay showed decreased re-formation norepinephrine. It is suggested that inhibition DBHenzyme may be involved in delayed psychosedative effect, but not short-term electrophysiological changes.
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