On the mechanism of action of carbonic anhydrase
作者： R.H. Prince , P.R. Woolley
DOI: 10.1016/0045-2068(73)90034-5
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摘要: Abstract The catalytic mechanism of the enzyme carbonic anhydrase has recently been subject renewed debate. generally accepted picture enzyme's action thrown into doubt by new evidence derived from spectroscopic techniques. In this paper some points conflict are examined and degree is assessed to which incompatible with previously held CA action. Reinterpretations put forward mechanisms proton transfer between solution detailed ligand displacement at zinc ion. These show that no means disproved remains plausible.
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