作者: Jeffrey G. Neal , Sunil J. Patel , John S. Kulbersh , J. David Osguthorpe , Rodney J. Schlosser
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摘要: BACKGROUND The aim of this study was to compare three different techniques for transsphenoidal pituitary surgery: (1) sublabial transseptal approach with microscopic resection, (2) transnasal endoscopic and (3) resection. METHODS We performed a retrospective review 50 surgeries by the same neurosurgeon. Demographic, radiographic, clinical data were collected. RESULTS Fifteen patients underwent tumor 21 14 completely technique. There total 20 complications in group, 13 complications, 6 complications. Cerebrospinal fluid leak incidence 53% approaches, 47% transnasal, 28% patients. Diabetes insipidus encountered 33% 5% 7% approaches. Lumbar drains required 40% 38% Nasal packing used 100% approaches 0% Mean recurrence rate follow-up 6.6% (50 months), 9.5% (11 (7 months). Average hospital stay 8.3, 6.2, 3.4 days, respectively (p < 0.05). CONCLUSION Transsphenoidal surgery has evolved over past several decades, because advances technology have been catalyst minimally invasive surgeries. Less such as resection .technique less morbidity shorter than traditional Continued is needed confirm long-term benefits similar rates.