An evaluation of the time dependence of the anisotropy of the water diffusion tensor in acute human ischemia.

作者: Fernando Zelaya , Neil Flood , Jonathan B Chalk , Deming Wang , David M Doddrell

DOI: 10.1016/S0730-725X(98)00192-1

关键词:

摘要: We have performed MRI examinations to determine the water diffusion tensor in brain of six patients who were admitted hospital within 12 h after onset cerebral ischemic symptoms. The been carried out immediately admission, and thereafter at varying intervals up 90 days post admission. Maps trace tensor, fractional anisotropy lattice index, as well maps blood perfusion parameters, generated quantitatively assess character infarcted area. In with significant deficits substantial lesion volume changes, four cases, our measurements show a monotonic decrease function time. propose that retrospective analysis this quantity, combination tissue segmentation maps, may be used future studies severity event.

参考文章(35)
A. Baethmann, F. V. Rosen, F. Staub, A. Neu, M. Zimmer, O. Kempski, Molecular mechanisms of glial swelling in vitro. Neurochemical Pathology. ,vol. 9, pp. 109- 125 ,(1988) , 10.1007/BF03160357
P.J. Basser, J. Mattiello, D. LeBihan, MR diffusion tensor spectroscopy and imaging. Biophysical Journal. ,vol. 66, pp. 259- 267 ,(1994) , 10.1016/S0006-3495(94)80775-1
Peter van Gelderen, Marloes H. M. de Vleeschouwer, Daryl DesPres, James Pekar, Peter C. M. van Zijl, Chrit T. W. Moonen, Water diffusion and acute stroke. Magnetic Resonance in Medicine. ,vol. 31, pp. 154- 163 ,(1994) , 10.1002/MRM.1910310209
Roger P. Woods, Simon R. Cherry, John C. Mazziotta, Rapid automated algorithm for aligning and reslicing PET images. Journal of Computer Assisted Tomography. ,vol. 16, pp. 620- 633 ,(1992) , 10.1097/00004728-199207000-00024
Daisy Chien, Richard B Buxton, Kenneth K Kwong, Thomas J Brady, Bruce R Rosen, None, MR diffusion imaging of the human brain. Journal of Computer Assisted Tomography. ,vol. 14, pp. 514- 520 ,(1990) , 10.1097/00004728-199007000-00003
Karl-Olof Löuvbld, Alison E. Baird, Gottfried Schlaug, Andrew Benfield, Bettina Siewert, Barbara Voetsch, Ann Connor, Cara Burzynski, Robert R. Edelman, Steven Warach, Ischemic lesion volumes in acute stroke by diffusion-weighted magnetic resonance imaging correlate with clinical outcome. Annals of Neurology. ,vol. 42, pp. 164- 170 ,(1997) , 10.1002/ANA.410420206
P. A. Barber, D. G. Darby, P. M. Desmond, Q. Yang, R. P. Gerraty, D. Jolley, G. A. Donnan, B. M. Tress, S. M. Davis, Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI Neurology. ,vol. 51, pp. 418- 426 ,(1998) , 10.1212/WNL.51.2.418
H. L. Lutsep, G. W. Albers, A. Decrespigny, G. N. Kamat, M. P. Marks, M. E. Moseley, Clinical utility of diffusion-weighted magnetic resonance imaging in the assessment of ischemic stroke Annals of Neurology. ,vol. 41, pp. 574- 580 ,(1997) , 10.1002/ANA.410410505
M E Moseley, Y Cohen, J Kucharczyk, J Mintorovitch, H S Asgari, M F Wendland, J Tsuruda, D Norman, Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology. ,vol. 176, pp. 439- 445 ,(1990) , 10.1148/RADIOLOGY.176.2.2367658
Robert Turner, James Pekar, Nichoias Patronas, Denis Le Bihan, Philippe Douek, MR color mapping of myelin fiber orientation Journal of Computer Assisted Tomography. ,vol. 15, pp. 923- 929 ,(1991) , 10.1097/00004728-199111000-00003