Evolution of water diffusion and anisotropy in hyperacute stroke: significant correlation between fractional anisotropy and T2.

摘要: BACKGROUND AND PURPOSE: We hypothesized that, in acute cerebral ischemic stroke, anisotropic diffusion increases if T2 signal intensity is not substantially elevated and decreases once hyperintensity becomes apparent. Our purpose was to correlate fractional anisotropy (FA) measurements with the clinical time of stroke onset, apparent coefficients (ADC), intensity. METHODS: Tensor diffusion-weighted images (DWIs) 25 patients were obtained within 12 hours symptom onset. Trace DWIs, ADCs, FAs, echo-planar T2-weighted (T2WI) generated. Stroke contralateral normal volumes interest (VOIs) outlined on DWIs projected onto inherently coregistered ADC map, FA T2WI. Mean VOIs compared for relatives change ADC, FA, T2WIs. RESULTS: A significant negative correlation observed between signal-intensity (r = −0.61, P .00009). trend onset found −0.438, .025). No values −0.302, .134). The mean reduction ipsilateral volume 31% ± 11 side. CONCLUSION: Change inversely correlated and, a lesser extent, but it well stage.