MR cholangiography in orthotopic liver transplantation: sensitivity and specificity in detecting biliary complications

作者: Piero Boraschi , Francescamaria Donati , Roberto Gigoni , Alessia Volpi , Simonetta Salemi

DOI: 10.1111/J.1399-0012.2009.01190.X

关键词:

摘要: Boraschi P, Donati F, Gigoni R, Volpi A, Salemi S, Filipponi Falaschi F. MR cholangiography in orthotopic liver transplantation: sensitivity and specificity detecting biliary complications. Clin Transplant 2010: 24: E82–E87. © 2009 John Wiley & Sons A/S. Abstract:  Background:  To assess the diagnostic value of magnetic resonance (MRC) when evaluating complications a large series transplants. Methods:  One hundred twenty-nine patients prospectively underwent (MR) imaging at 1.5-T device after transplantation (OLT). After preliminary acquisition axial T1- T2-weighted images, MRC involved respiratory-triggered, thin-slab (2 mm), heavily fast spin-echo breath-hold, thick-slab (10–50 mm), single-shot sequences. images were blindly evaluated by two experienced readers conference to determine anatomy presence complications, whose final diagnosis was based on endoscopic retrograde cholangiography, percutaneous trans-hepatic integrating clinical follow-up with ultrasound and/or findings. Results:  Biliary found 60 (46.5%) represented ischemic-type lesions (n = 21); anastomotic strictures (n = 13); non-anastomotic (n = 5); associated lithiasis (n = 6); papillary dysfunctions (n = 9). The sensitivity, specificity, positive predictive value, negative reviewers for detection all types OLT 98%, 94%, respectively. Conclusions:  is reliable technique post-OLT should be recommended before planning therapeutic interventions.

参考文章(21)
David S. Zimmon, David B. Falkenstein, Charles Riccobono, Bernard Aaron, Complications of endoscopic retrograde cholangiopancreatography. Analysis of 300 consecutive cases. Gastroenterology. ,vol. 69, pp. 303- 309 ,(1975) , 10.1016/S0016-5085(19)32569-7
T Laor, F A Hoffer, J P Vacanti, M M Jonas, MR cholangiography in children after liver transplantation from living related donors. American Journal of Roentgenology. ,vol. 170, pp. 683- 687 ,(1998) , 10.2214/AJR.170.3.9490953
Rungsun Rerknimitr, Stuart Sherman, Evan L. Fogel, Cem Kalayci, Lawrence Lumeng, Naga Chalasani, Paul Kwo, Glen A. Lehman, Biliary tract complications after orthotopic liver transplantation with choledochocholedochostomy anastomosis: endoscopic findings and results of therapy. Gastrointestinal Endoscopy. ,vol. 55, pp. 224- 231 ,(2002) , 10.1067/MGE.2002.120813
V. Meersschaut, K. J. Mortelé, R. Troisi, H. Van Vlierberghe, M. De Vos, L. Defreyne, B. de Hemptinne, M. Kunnen, Value of MR cholangiography in the evaluation of postoperative biliary complications following orthotopic liver transplantation. European Radiology. ,vol. 10, pp. 1576- 1581 ,(2000) , 10.1007/S003300000379
T. Kok, A. Van der Sluis, J. P. Klein, E. J. Van der Jagt, P. M. J. G. Peeters, M. J. H. Slooff, C. M. A. Bijleveld, E. B. Haagsma, Ultrasound and cholangiography for the diagnosis of biliary complications after orthotopic liver transplantation: A comparative study Journal of Clinical Ultrasound. ,vol. 24, pp. 103- 115 ,(1996) , 10.1002/(SICI)1097-0096(199603)24:3<103::AID-JCU1>3.0.CO;2-L
A Laghi, P Pavone, C Catalano, M Rossi, V Panebianco, D Alfani, R Passariello, MR cholangiography of late biliary complications after liver transplantation. American Journal of Roentgenology. ,vol. 172, pp. 1541- 1546 ,(1999) , 10.2214/AJR.172.6.10350286
A Fleck, M.L Zanotelli, M Meine, A Brandão, I Leipnitz, E Schlindwein, A Cassal, T Grezzana, C Marroni, G.P.C Cantisani, R.R Santos, Biliary tract complications after orthotopic liver transplantation in adult patients. Congress of the Brazilian Organ Transplant Association. ,vol. 34, pp. 519- 520 ,(2002) , 10.1016/S0041-1345(02)02615-5
M T Keogan, V G McDermott, S K Price, V H Low, J Baillie, The role of imaging in the diagnosis and management of biliary complications after liver transplantation. American Journal of Roentgenology. ,vol. 173, pp. 215- 219 ,(1999) , 10.2214/AJR.173.1.10397129
P. Boraschi, F. Donati, R. Gigoni, L. Urbani, M. Femia, M.C. Cossu, F. Filipponi, F. Falaschi, Ischemic-type biliary lesions in liver transplant recipients: evaluation with magnetic resonance cholangiography Transplantation Proceedings. ,vol. 36, pp. 2744- 2747 ,(2004) , 10.1016/J.TRANSPROCEED.2004.09.038
Piero Boraschi, Giovanni Braccini, Roberto Gigoni, Giorgio Sartoni, Emanuele Neri, Franco Filipponi, Franco Mosca, Carlo Bartolozzi, Detection of biliary complications after orthotopic liver transplantation with MR cholangiography Magnetic Resonance Imaging. ,vol. 19, pp. 1097- 1105 ,(2001) , 10.1016/S0730-725X(01)00443-X