Utility of Interferon-γ Release Assay Results to Monitor Anti-Tubercular Treatment in Adults and Children

作者: Elena Chiappini , Francesca Fossi , Francesca Bonsignori , Sara Sollai , Luisa Galli

DOI: 10.1016/J.CLINTHERA.2012.03.006

关键词:

摘要: Background: Interferon- release assays (IGRAs), including the commercially available T-SPOT.TB, QuantiFERON-TB Gold (QFT-G), and QuantiFERONTB In-Tube (QTF-G-IT), enable detection of circulating T lymphocytes responsive to specific Mycobacteriumtuberculosisantigens.Studiesofthepotentialroleof serial IGRAs for assessment response anti-tubercular therapy are accumulating. Objective: The objective this systematic review was evaluate potential clinical utility in therapy. Methods: We conducted a literature search

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