Carbapenem-Resistant Enterobacteriaceae Infections in Patients on Renal Replacement Therapy.

摘要: Background Patients on chronic intermittent renal replacement therapy (RRT) are at risk for infection with carbapenem-resistant Enterobacteriaceae (CRE). However, the impact of RRT outcomes after CRE infections remains to be defined. Here we perform a comparison CRE-infected patients preserved function compared RRT. Methods Cases and controls were defined from prospective cohort Consortium Resistance against Carbapenems in Klebsiella other (CRACKLE). as hospital admission, while serum creatinine <2 mg/dL not receiving admission. Risk factors 28-day in-hospital mortality assessed using multivariable logistic regression. An ordinal ranking by desirability analysis was performed. Results more likely have diabetes mellitus cardiac disease than controls. Urinary sources less common group. In patients, increased controls: 22/71 (31%) vs 33/295 (11%). remained significantly associated adjustment source infection, prehospitalization origin, severity illness (adjusted odds ratio, 2.27; 95% confidence interval [CI], 1.09-4.68; P = .03). Using univariable outcome analysis, status 68% (95% CI, 61%-74%) chance worse disposition outcome. Conclusions Chronic is 28 days.