Application of fluorescence polarization immunoassay for determination of carbamazepine in wastewater

作者: Lidia Oberleitner , Ursula Dahmen-Levison , Leif-Alexander Garbe , Rudolf J. Schneider

DOI: 10.1016/J.JENVMAN.2017.01.063

关键词:

摘要: Carbamazepine is an antiepileptic drug that can be used as a marker for the cleaning efficiency of wastewater treatment plants. Here, we present optimization fast and easy on-site measurement system based on fluorescence polarization immunoassay successful application to wastewater. A new monoclonal highly specific anti-carbamazepine antibody was applied. The automated assay procedure takes 16 min does not require sample preparation besides filtration. recovery rates carbamazepine in samples were between 60.8 104% with good intra- inter-assay coefficients variations (less than 15 10%, respectively). This enables

参考文章(43)
Victoria Osorio, Aitor Larrañaga, Jaume Aceña, Sandra Pérez, Damià Barceló, Concentration and risk of pharmaceuticals in freshwater systems are related to the population density and the livestock units in Iberian Rivers. Science of The Total Environment. ,vol. 540, pp. 267- 277 ,(2016) , 10.1016/J.SCITOTENV.2015.06.143
Robert Banaschik, Petr Lukes, Helena Jablonowski, Malte U. Hammer, Klaus-Dieter Weltmann, Juergen F. Kolb, Potential of pulsed corona discharges generated in water for the degradation of persistent pharmaceutical residues Water Research. ,vol. 84, pp. 127- 135 ,(2015) , 10.1016/J.WATRES.2015.07.018
Rosa Freitas, Ângela Almeida, Adília Pires, Cátia Velez, Vânia Calisto, Rudolf J. Schneider, Valdemar I. Esteves, Frederick J. Wrona, Etelvina Figueira, Amadeu M.V. M. Soares, The effects of carbamazepine on macroinvertebrate species: Comparing bivalves and polychaetes biochemical responses Water Research. ,vol. 85, pp. 137- 147 ,(2015) , 10.1016/J.WATRES.2015.08.003
Thomas A Ternes, Occurrence of drugs in German sewage treatment plants and rivers Water Research. ,vol. 32, pp. 3245- 3260 ,(1998) , 10.1016/S0043-1354(98)00099-2
Lidia Oberleitner, Sergei A. Eremin, Andreas Lehmann, Leif-Alexander Garbe, Rudolf J. Schneider, Fluorescence polarization immunoassays for carbamazepine – comparison of tracers and formats Analytical Methods. ,vol. 7, pp. 5854- 5861 ,(2015) , 10.1039/C5AY00617A
W. Y. Lin, M. L. Pan, H. Y. Wang, Y. O. Su, P. W. Huang, Analysis of carbamazepine serum by differential pulse voltammetry (DPV) and comparison with fluorescence polarization immunoassay (FPIA): an animal study Medicinal Chemistry Research. ,vol. 21, pp. 4389- 4394 ,(2012) , 10.1007/S00044-012-9981-5
Adriano Joss, Elvira Keller, Alfredo C. Alder, Anke Göbel, Christa S. McArdell, Thomas Ternes, Hansruedi Siegrist, Removal of pharmaceuticals and fragrances in biological wastewater treatment. Water Research. ,vol. 39, pp. 3139- 3152 ,(2005) , 10.1016/J.WATRES.2005.05.031
Yongjun Zhang, Sven-Uwe Geißen, Carmen Gal, Carbamazepine and diclofenac: removal in wastewater treatment plants and occurrence in water bodies. Chemosphere. ,vol. 73, pp. 1151- 1161 ,(2008) , 10.1016/J.CHEMOSPHERE.2008.07.086
C. Nadejde, M. Neamtu, V.-D. Hodoroaba, R.J. Schneider, A. Paul, G. Ababei, U. Panne, Green Fenton-like magnetic nanocatalysts: Synthesis, characterization and catalytic application Applied Catalysis B-environmental. ,vol. 176, pp. 667- 677 ,(2015) , 10.1016/J.APCATB.2015.04.050
David S. Smith, Sergei A. Eremin, Fluorescence polarization immunoassays and related methods for simple, high-throughput screening of small molecules Analytical and Bioanalytical Chemistry. ,vol. 391, pp. 1499- 1507 ,(2008) , 10.1007/S00216-008-1897-Z